CBD and The Brain Home › Forums › CBD and The Brain This topic has 1 reply, 2 voices, and was last updated 5 years, 1 month ago by dev7. Viewing 1 post (of 1 total) Author Posts March 2, 2019 at 2:15 pm #1676 PrincessMMember CBD works on both CB1 and CB2 receptors and interacts with the brain and nervous system. A chemical called anandamide in higher levels regulates pain, and CBD may help in metabolizing it, so it can be used to reduce feelings of pain. Author Posts Viewing 1 post (of 1 total) You must be logged in to reply to this topic. Log In Username: Password: Keep me signed in Log In