The Three Main THC Analogues and The Phytocannabinoid Epidiolex

[Momma Mia]

The FDA has approved three synthetic cannabinoids, and one plant derived cannabinoid. The first three are also known as analogues, which are the synthetic, laboratory created versions. These are: Marinol and Syndros, of which their chemical or generic formulae are both dronabinol, and Cesamet, or Nabilone. These are THC, tetrahydrocannabinol, synthetics, and are indicated to treat a broad variety of conditions.

Some of these disorders which they can successfully assist with relieving are anorexia, associated with weight loss, in adult AIDS patients. The THC synthetics interact with the brain receptor sites to stimulate appetite. In addition, these compounds can combat the nausea and vomiting associated with chemotherapy for cancer. Dronabinol and Cesamet can be used by adult patients for whom the traditional antiemetic have not worked. Honestly, I wish that on a personal level, that I could have utilized these substances back in 2002, when I had a very potent chemotherapy, for which the antiemetic I was given, called Kytril, granisetron Hcl, did very little to quell the severe vomiting.

The phytocannabinoid, Epidiolex, as we have discussed in the forum, gained FDA approval to be classified as a Schedule 1 drug to treat rare forms of epilepsy that have not responded to conventional treatment, and it also has been effective for symptoms of tuberous sclerosis complex.

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